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  1. #25
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    A) I do not sell or advertise for ANY company. I have personally tested products from companies interested in knowing if the compounds they are buying(mostly from China) are real or counterfeit, and how is it that the pharma igf-1 is 10x the price of what is seen being sold by online peptide companies.
    My point was, whether they are synthetic or from recombinant DNA, they can still bind to the receptor, and what is important is how much actually binds. If you have only a 10% binding affinity , then 100mcg would be required to get 10mcg to bind. A blood test for igf 1 may well reveal high blood serum levels, but says nothing about how much bound to the receptor (if any) This is why so many people see no results. Most of what is out there is garbage. Receptor grade igf 1-lr3 is about 35,000/gram
    or 250 to 600$ per mg . The first thread suggested that only rDNA igf is functional, and that isn't the case. Synthetic igf will bind also. NONE of these peptide companies manufacture the peptides, they buy it from China, label it and re-sell it.
    The only way to really know what you have is to get it tested.

  2. #26
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    Thanks Jesus, but I don't think he would go tell people to "fuk"themselves
    he would probably go to college and get an education first

  3. #27
    Elite BigSwolePump's Avatar
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    Again, what is your point?
    Don't listen to me. I make things up as I go.

  4. #28
    Elite Redrum1327's Avatar
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    You're not helping your case. Anyone with a brain will have their products tested to make sure they're not throwing away money over and over. You basically just stated everything we already knew and had already been mentioned. Thanks for your .02 tho
    "Herms like the Walmart greeter of the Mods" - DF
    Strength First Boston !!!!
    TRUMP2016

  5. #29
    Administrator PillarofBalance's Avatar
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    Quote Originally Posted by Analyticchem View Post
    A) I do not sell or advertise for ANY company. I have personally tested products from companies interested in knowing if the compounds they are buying(mostly from China) are real or counterfeit, and how is it that the pharma igf-1 is 10x the price of what is seen being sold by online peptide companies.
    My point was, whether they are synthetic or from recombinant DNA, they can still bind to the receptor, and what is important is how much actually binds. If you have only a 10% binding affinity , then 100mcg would be required to get 10mcg to bind. A blood test for igf 1 may well reveal high blood serum levels, but says nothing about how much bound to the receptor (if any) This is why so many people see no results. Most of what is out there is garbage. Receptor grade igf 1-lr3 is about 35,000/gram
    or 250 to 600$ per mg . The first thread suggested that only rDNA igf is functional, and that isn't the case. Synthetic igf will bind also. NONE of these peptide companies manufacture the peptides, they buy it from China, label it and re-sell it.
    The only way to really know what you have is to get it tested.
    This makes your point a hell of a lot more clear then your first post.

    So this thread started pretty much as an experiment by Cobra Strike. For a couple years we have been saying there isn't a chance that cheap Chinese and research chemical company IGF is legitimate quality regardless of synthetic or recombined.
    Rest in Peace Robot Lord. First round of Natty Boh is on me when I make it up there with you brother.

  6. #30
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    The point was in response to what started the thread, that ONLY Igf made from recombinant DNA (e.coli) is biologically active..or will bind. The abstract is from a published medical article in which it clearly demonstrates that synthetic igf will bind to the receptors, quite well actually.

    .ncbi.nlm.nih.gov/m/pubmed/2962574/




    Look up solid phase peptide synthesizers or microwave peptide synthesizers. This is how peptides are made in the lab, but are efficient up to Amino acid sequences(residues) of 60.
    Igf is 70 , igf 1 lr3 83.
    What the Chinese do is synthesize smaller pieces , say 20 aa's long and basically "glue" them together. This process leaves impurities and unwanted residues behind. They may have the sequence correct, but this is just the linear chain.
    Think of a rubber band, now begin twisting it until it "balls" up..this is the proteins tertiary structure and that is how the protein exists in its natural state , and that is how it fits into the receptor, like a lock and a key.
    To make rDNA is a much larger investment and only a few companies in China have these reactors, and they don't sell on the black market.

    It won't let me post complete links but here is part of it
    .asianscientist.com/2014/10/in-the-lab/revolutionary-tool-joining-peptides/

    I have tested many that have the sequence correct, but most are very impure, less than 70% , and the most important test, binding affinity, they are worthless.

    But again , I just read that this guy , moppy? started the discussion stating that synthetic igf doesn't work, and the scientific evidence shows that it does.
    I only tried to share what I know, as I've studied peptides for a number of years.

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