Female experience with Ostarine - holy suppression!

Death

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Cite that evidence.
exactly - since my experience I’ve gone on to find anecdotal accounts with lab work on Reddit of men getting their natural T level dropping by as much as 75% while on Ostarine!

I wonder how many of those who didn’t have their T drop weren’t getting real Ostarine for example.
 

Death

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It seems like MK-2866 is either suppressive for females, or the OP could be an outlier.

Hmm I wonder. What if what I got wasn’t Ostarine? Then what was it? You would think if it was one of the more suppressive SARMs that the supplier sent instead, then I’d have gained some muscle and had something to show for all this... I’m not about to go get the Ostarine I got lab tested or anything like that, plus I already pitched it after my experience.
 

MrRippedZilla

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For those following along for more info, and because I'm in a giving mood...

It is impossible to have the magic of activating androgen receptors without the suppression that results from that activation. Period. The only way to limit that suppression is to use ineffective & inefficient doses, which would be an exercise in futility. This very simple fact applies to sarms, aas, prohormones and everything else that actually works.

Here we have a human clinical trial using Ostarine at doses up to 3mg - tiny doses. The data within shows clear suppression for women (FSH/LH crashing) that trended with dosage but no impact on men. Why? Because 3mg was a significant dose for women but was not for men. That's it. You'd see similar results with anavar, primo, test, and every other compound under the sun. Women will experience suppression at much lower doses because they need much lower doses to obtain the benefits. Men will not experience significant suppression at these lower doses because those lower doses aren't doing anything of note. It's all part of the same puzzle and the idea that you can avoid the suppression while obtaining the benefits is, to be frank, bullshit.

You'll also note that 20% of those subjects had elevated ALT levels, which indicates stress on the liver. At just 3mg. This is why sarms are garbage drugs. Compared to traditional AAS choices, you're getting something that is understudied, has similar side effects, and worse results. And they pop up in drug tests. I have no idea why anyone, once they understand this, would waste money on them.
 
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I just wanted to share my personal experience with Ostarine.

LABWORK

I had baseline labwork done before starting, my testosterone level was 10, which is pretty low anyway even for a woman.

I took 10-12.5 mg of Ostarine every day for 4 weeks.

After 4 weeks I had labs drawn again and my testosterone dropped to 2!!!

Beware of the suppression! This is not a benign SARM. This is an insane amount of suppression considering the dose.

SIDE EFFECTS

Side effects were mostly sexual.

Please don’t be a pervert about the following information, and this is only being shared for the benefit of female body builders.

In the first week of Ostarine my libido went out of control high, and at baseline mine is already high as is. Clitoral sensitivity increased. It was awesome.

Week 2-end of week 3 felt pretty normal aside from increased appetite for some reason.

Then, around the end of week 3, I noticed orgasm threshold increased (meaning it was noticeably more difficult to orgasm, big bummer). I immediately suspected suppression. Libido was okay throughout all this.

When I stopped taking it I had a headache for, no joke, a full six days straight. Not a migraine, just a tension headache, 4-5/10 pain level. I very very rarely get headaches and this was the only variable that changed. I also put on 3lb of water weight in 24 hours the day I stopped it. My belly still feels kind of bloated.

Looking forward to my hormones bouncing back to say the least!


VERDICT

I wanted to try the SARM for just a month in order to see what it could do for me and it wasn’t worth it at all for me. I wouldn’t recommend it.

Did I look any different? No!

Am I stronger? Some of my lifts progressed a little bit but this likely would have happened without Ostarine either.

I don’t think I gained much muscle. Definitely not more than I would have just going it alone without the SARM. I tracked every calorie as always and I weigh all my food, I ate at maintenance the first 2 weeks on it, then shifted to a very slight surplus the second 2 weeks - maybe 100 calories over maintenance per day.



I am considering taking some DHEA as a possible PCT to help my T levels go up.

My next step will be to see a female hormone replacement specialist in the next 3-6 months. My T is low as is and my estradiol is really low, I’m way too young to have these geriatric-looking labs. Some may be due to my birth control but definitely not all!

I work in healthcare but I am not strong in endocrinology so I look forward to the expert opinion and will keep y’all updated.

Not surprising and consistent with clinical trials. The only SARM worth considering would be LGD 4033, decent clinical data and less liver toxicity than osterine, but there is a case report of cholestatis in a couple guys using LGD and RAD. They didn't report how much however. Having said that, any female should not consider a SARM if you're still interested in having kids. We just don't know the long term effects of any SARM and only taken with T as it will lower SHBG and increase free T, as a stand alone not worth it. Way better off with either VAR or test esters (safest). We know from the trans lit that doses in the 80 - 100 mg/wk range do not cause any serious sides (liver, cardiovascular, stroke or cancer). Sure you'll virilize but that isn't life threatening and depends on dose and duration, and individual response. I have a female client, age 54, takes 50 mg TC sub-Q every 5 days. Has been on T for close to a year. Very few sides, libido and energy is great, a little hair growth and that's it. No hair loss, clitoral hypertrophy, acne, etc. and she is hard as nails and very muscular. A clear responder. Her T is legit from a hormone replacement doc. Pretty high dose, she loves it. Side effects vary, some have them on low doses of T others can handle much higher dosing. Look at Dr Glaser's work (hormonebalance.org/publications/). All depends on what you are willing to tolerate vs how you feel and look (physique). Some women are fine with a little deeper voice, they love the bigger clit (nuclear orgasms) and energy/feeling of well being and shaving a few hairs. Others freak out at the slightest change. IMO, if you don't want ANY virilization, don't take ANYTHING.
 

Blacktail

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My wife is on testosterone pellets. Been a month and she feels better and sex drive has gone up. Also sensitivity during sex has also greatly improved. She gets bloods done next month. I will post results when she gets them.
 
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Big Mikey

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This post is quite interesting. Birth control can adversely effect the endocrine system as well as the neurological system. Obviously so can PED's. A referral to an endocrinologist was a very wise move.
 
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Depending on the dosing, her total T at around 6 weeks post pellet will be about 300 - 350 ng/dl. From Glaser's papers and what the doc in our area sees. IMO, sc TC in low doses is more effective, easier to control blood conc and way cheaper than pellets. Endos won't touch T in a female, last medical professional you'd want to see for HRT (T) in a women. BCs elevated SHBG, often times long after they are stopped. Will crush free testosterone in a female.
 
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andy

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hope u ok now.
never was a big fan of SARMS
 

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