We know all exogenous steroids will suppress natural production. That is a basic truth of every available anabolic androgenic. Teaticular atrophy is a side effect of suppression. Some ppl never experience the atrophy while others expereince it to a large degree. That's one reason and the other is bc absorption of oral testosterone like andriol is much lower than injectable preparations. If you took 100mg of each, the injectable test would be much more readily absorbed so at similar doses you'd potentially expereince increased testicular atrophy. Andriol boosts test levels which will also increase aromatization which by itself would further limit natural testoaterone production. Your pituitary is not shutdown directly. It's a downstream effect bc when taking exogenous test like andriol it will ultimately inhibit the hypothalamus from producing GNrH which acts upon the pituitary. So pituitary shutdown is secondary to the hypothalamus.
If you've got the article please post it. I'd love to see it. And please don't let it be an article written by Joe Schmoe who has a column for Flex magazine or something. A published and peer reviewed study would be nice or something from Merck themselves.
Sorry for replying to an old topic but this is of much interest to me.
I am not allowed to post linkbut google"Merck leaflet Andriol"
From the official Merck leaflet:
Human Pharmacology
In healthy men daily oral doses of 160 mg/day for 14 days did not suppress plasma FSH and LH
levels nor pituitary responsiveness to stimulation by LHRH.
This is a replacement dose of Andriol.
With limited absorbtion rate of 7% of the 100mg testosterone contained in 160mg Andriol(4 caps),it translates to at least 7 mg testosterone daily in the bloodstream.
This equals a dose of about 100mg test-e given per 10 days.
Easy to find studies show that 100mg of injectable test a week brings LH FSH to a complete zero.
The non stop circulating effect of injected test is far more suppressive that the highs and lows/spikes that you get with Andriol. Also,the Andriol way of administration yields less estrogen conversion I presume.
All being said,I have a boatload of Andriols to try out(I have never taken it before).I will be doing blood work and reporting it.