Tadalafil (Cialis) improves lean mass and endothelial function in men

[CohibaRobusto]

https://pubmed.ncbi.nlm.nih.gov/28133708/

CONCLUSION: Daily tadalafil improved lean mass content in non-obese men probably via enhanced insulin secretion, estradiol reduction, and improvement of endothelial function in vivo. The in vitro increased myogenin and androgen receptor protein expression in skeletal muscle cells suggests a translational action of phosphodiesterase type-5 on this receptor.

https://www.reddit.com/r/steroids/comments/hqeyeh/discussion_tadalafil_cialis_improves_lean_mass/

I found this really interesting. I was not aware of the effect on insulin secretion or estradiol reduction.

Comments on the reddit post are good too.

 

[Flyingdragon]

Maybe it was all the sex the men were having while taking daily doses of the drug...

 

[dragon1952]

The in vitro increased myogenin and androgen receptor protein expression in skeletal muscle cells suggests a translational action of phosphodiesterase type-5 on this receptor.

I wonder if the same could be said re: viagra since they are both phosphodiesterase type-5

 

[Trump]

It also grows your pp to a size where it doesn’t fit anywhere. Hulksmash told me

 

[Bro Bundy]

its best used for just getting your dick hard

 

[Texan69]

It also grows your pp to a size where it doesn’t fit anywhere. Hulksmash told me

good ole hulksmash
apparently his finger can get cut off and grow back or something like that

 

[Grego]

does crushing them and snorting increase the effect, asking for a friend :32 (1):

 

[simplesteve]

does crushing them and snorting increase the effect, asking for a friend :32 (1):

Booty bump is the only way to really get the best effects

 

[Jin]

Booty bump is the only way to really get the best effects

Spoken like a true ex-con:32 (19):

 

[zeke42]

Nice. Just started using 5mg/day this week. Liking the lower blood pressure effect. Good to know there are other benefits.

 

[Sicwun88]

Taking 10mg a day enjoy all the benefits from BP to ass smashing!

 

[Rot-Iron66]

Helps w/ mass alright, caulk has vein-popping pumps. :32 (1):
Seriously though, I do 5 mg a day, awesome BP cure (for me) and always ready for fun time w/ wife...