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**First let me say i am totally ignorant to testosterone, peptides, and steroids in general. So i am asking here at the advice of pms i received after posting on both the TRT and Peptide subreddits because people said you guys would be more knowledgeable. **
I also copy/posted 5his from reddit to get more advice. I feel like i am being pulled in different directions from people who know the wcience but arnt my doctors
My research doctor said he hopes to bring my testosterone which is around the 100s to at the very least 700+ on a regular basis. (not sure what he wants my free value to be, but whatever coorelates with that). **Just in case its not elsewhere in this thread i am 5 foot 9, early 30s, and 302 pounds.
I also have high estradiol which is about 66, (quest range is normal below 39) so we are concerned about that. We talked about being put on an Aromitase inhinbitor but I have read bad things online and I'm not sure if I should do it? But obviously something is going on with that high of estradiol.
I also have low Vitamin d,25 at 16 (30-100 range), DESPITE, being on prescription strength supplements prescribed for a month. I believe they are 50,000 IU or so per week? But for some reason after a month my vitamin D didn't increase so my doctor is doubling the dosage.
My liver enzyme values AST and ALT are normal despite being fatty liver in the past. Through diet and excercise those level are expected to lower.
Here are some of my other labs that are concerning as to why GH peptides and anti-inflammatory peptides are recommended for me.
First, I would be given glutathione and anti-inflammatory peptides after my first 3 months of testosterone to make sure my cholesterol and triglycerides are reduced to more normal levels and measure the lost of weight. he doesn't want to do the growth hormone peptides if this doesn't happen
Bloodwork
Cholesterol total-206
HDL-31
Triglycerides-261 (Some of the peptides specifically target triglycerides and mine seem to be extremely high. What can I do diet wise to reduce triglycerides in a fast and thorough way that is sustainable and keep it off?
LDL-135
CHOL/HDLC RATIO-6.6
NON HDL CHOLESTEROL-175
LDL PARTICLE NUMBER-1732 (HIGH RISK>1409)
LDL SMALL-507 (HIGH >219) LDL MEDIUM-459 (HIGH >301) HDL LARGE-4168 (HIGH < 5353)
LDL PATTERN-B (RISK HIGH =B) LDL PEAK SIZE-213.3 (HIGH <217.4)
APOLOPOPROTEIN B-120 (<90)
LIPOPROTEIN(a)-13 (good range, <75)
HS CRP Cardio IQ- 5.8 (optimal <1)
LP PLA2 ACITIVITY-120 (good range, <123)
So those are my additional labs if those help, i will add those to my main post as well.
The doctors at John's hopkins don't know right now why I am unable to build muscle mass or lose weight. I was put on a number of extreme dietary changes. First and foremost my weight loss is obviously most important since i am over 300 pounds at 5 foot 9. They started with 1000 calories a day on a intermittent fasting of 8 hours eating and 16 hours fasting for 3 months. I had some results in the loss of 5 - 10 pounds but I should lose far more than that.
They will be doing a full genetic workup to determine and rule out and genetic problems and pituatary gland issues that prevent me from losing weight. but these results wont be back for some time.
The rational regarding the growth hormone peptides is to prevent burning muscle that I do have and so I can increase calories little by little and increase weight lifting so I can create muscle to burn fat. A sort of "aid" if you will.
I am currently being treated with the following...
1. i just got my HCG injection that calls for... OLY HCG 10,000 IU PWVL VIAL, MIX WITH 5ML DILUENT, INJECT 0.25CC SUBCUTANEOUDLY 3 TIMES PER WEEK.
**MY MAIN ISSUE IS IF THIS IS SAFE AND BENEFICISL IN SOME WAY RRGARDLESS OF PRICE BECAUSE I SAVED UP FOR IT. IT IS EXPENSIVE, HOWEVER, BUT I AM WILLING TO GO THROUGH HOPKINS RESEARCH HOSPITAL TO HELP UNDERSTAND AND TREAT MY INABILITY TO LOSE WEIGHT (AND GAIN WEIGHT) AS WELL AS NOT GAIN MUSCLE FROM HEAVY WEIGHT TRAINING**
2.Along with this i will be taking 80mg twice weekly of testosterone (received 160mg two days ago and received an immediate mood boost). As well as the glutathione at some point here I believe.
Now the next step would be to be put on Anti Inflammatory Peptides -2 weeks or 4 weeks, There are 2 daily injections and a pill you take daily Thymosin Alpha 1, Thymosin Beta 4, and BPC 157.
3. The last step would be growth hormone peptides
CJC 1295 is an injection done 3times a day, 6 days a week. Tesamorelin is a 1 time daily injection 6 days a week.
My doctors want me to be on these peptides first before i try the growth hormone and the Tesamorelin.
So obviously i am new and need guidance. Sorry for long post. But i need guidance and help from others who have been through this
Thanks so much and have a great day!