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  1. #1
    Elite ken Sass's Avatar
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    good article on exemestane (aromisan)

    Exemestane In Men. Image
    Exemestane In Men
    Exemestane is a generic. Since the patent for Aromasin has expired, its generic, Exemestane, is available at the moment. How does Examestane work in men? Exemestane is an aromatase inhibitor. It is steroid that benefits over other anti-estrogens. In order to understand the its priorities and function of Exemestane in men, let study the results of a research. Some healthy men (1426 years of age) were enrolled in the study. In a cross-over study, 12 of them were randomly assigned to 25 and 50 mg of Exemestane daily for 10 days with a 14-d washout period. Blood was tested before and 24 hours after the last dose of each treatment period. Exemestane suppressed plasma estradiol comparably with either dose (25 mg, 38% (P ? 0.002); 50 mg, 32% (P ? 0.008)), with a reciprocal increase in testosterone concentrations (60% and 56%; P ? 0.003 for both). Plasma lipids and IGF concentrations were unaffected by treatment. The value of the 25-mg dose showed the highest exemestane concentration was 1 hour after administration, indicating rapid absorption. The terminal half-life was aproximately 9 hours. So, it was made a conclusion that Exemestane is an effective aromatase inhibitor in men.

    Some other researches related to function of Exemestane in men were also conducted. There were treated men who had different functional mutations. Male patients with functional mutations in the estrogen receptor gene or the aromatase gene have demonstrated continued growth into adulthood, tall stature, and osteopenia. This information has lead to the investigation of pharmacologically induced estrogen deficiency as an adjunct in delaying epiphysis fusion in men who had short stature and potentially increasing final adult height.

    According to the results of different researches some confirmations were done:

    - estrogens do not contribute significantly to the changes in body composition and protein in men;

    - the level of aromatase inhibition which a man receives by using Exemestane does not negatively influence on bone calcium metabolism.

    It is important to know how Exemestane works in order to take the proper dose and to know with which other drugs men may combine it. Exemestane is an aromatase inhibitor, it means that it binds itself with aromatase enzymes and since Exemestane does it permanently, it disables the enzyme and destroys it.

    Exemestane's half life in body of men is very short, it lasts approximately 9 hours, then it is quickly eliminated. But it is necessary to mention that Exemestane works very quickly and effective. As soon as it enters your bloodstream it quickly destroys 80-90% of the aromatase enzymes in your body. So it is possible to co confirm that it is effective in maintaining significant reductions in estrogen for up to 72 hours after a single 25mg dose. You should know that estrogen levels begin to increase again after your body has begun to make new aromatase enzymes to replace the ones which were destroyed by Exemestane.

    There have been done some researches related to Exemestane in men in the sphere of pharmacokinetics. The results of the research are following:

    - 24 hours after one 25mg dose estrogen levels are reduced by 70-80%;

    - 72 hours later estrogen levels are still 40% below the baseline;

    - 120 hours after initial dose estrogen levels return to baseline.

    If men want to take Examestane, they may be conducted by the results of this research that shows the optimal dose of taking Exemestane. It is recommended to take 25 mg of Exemestane daily.

    Let enumerate the good changes that can be produced in body of men by Exemestane:

    - stopping gynecomastia completely;

    - powerful bloat-reduction effects;

    - increasing of IGF;

    - increasing of libido;

    - no changes in lipid profile;

    - effectiveness on PCT;

    - increasing of testosterone.

    Side effects of Exemestane in men are following:

    - hot flashes;

    - headaches;

    - fatigue;

    - Insomnia;

    - depression;

    - high blood pressure;

    - nausea;

    - vomiting;

    - Increasing of appetite;

    - diarrhea;

    - Constipation;

    - abdominal pain;

    - difficulty breathing.

    If men are going to use this drug, they should know how it works, what possible changes, good results and side effects Exemestane can produce in men.


    taken from http://steroids-blog.bestanabolicsto...ane-in-men.php

  2. #2
    Elite ken Sass's Avatar
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    Re: good artical on exemestane (aromisan)

    i personally think this dose 25mg a day is pretty high, a lot of other things i have looked at say 12.5 mg a day or even every other day is g2g. all depends on your system i think

  3. #3
    Elite TheLupinator's Avatar
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    Re: good artical on exemestane (aromisan)

    Nice find. Aroma has always been my AI of choice, now if I can only get my boy to make his own.. it's hard to trust these Res-Chem companies
    I <3 My Source

  4. #4
    Elite PillarofBalance's Avatar
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    good artical on exemestane (aromisan)

    12.5mg per day is too much IMO. I didn't see where it said 25mg per day although I only skimmed this.

    My joints would be glass.
    "Overzealous dosing" -Jin

    Rest in Peace Robot Lord. First round of Natty Boh is on me when I make it up there with you brother.

  5. #5
    Elite LeanHerm's Avatar
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    Re: good artical on exemestane (aromisan)

    Well company's like mp has caps that are 25mg which I take it eod and I'm golden

  6. #6
    Elite. SFGiants's Avatar
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    Re: good artical on exemestane (aromisan)

    12.5mg M/W/F has been a charm for me
    Knock Em Down and Keep Em Down!

  7. #7
    Elite gymrat827's Avatar
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    Re: good article on exemestane (aromisan)

    25mg eod for me. or 2x a wk if its a low low dose of tes.

  8. #8
    Senior Moderator NbleSavage's Avatar
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    Re: good artical on exemestane (aromisan)

    Originally Posted by SFGiants View Post
    12.5mg M/W/F has been a charm for me
    Right there with you, Mate.

  9. #9
    Elite 63Vette's Avatar
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    Re: good article on exemestane (aromisan)

    12.5 mg eod for the Vettester.... Hits me in the sweet spot every time.

    Respect,
    Vette
    Hung like Einstein and Smart as a Mule.

  10. #10
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    Re: good article on exemestane (aromisan)

    Def switching from adex to aro the plus sides of it are alot better. But I will say in the past if i take more then 12.5mg a day i get severe side effects

  11. #11
    Elite ken Sass's Avatar
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    Re: good article on exemestane (aromisan)

    i am going e2d for awhile

  12. #12
    Elite Jada's Avatar
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    Re: good article on exemestane (aromisan)

    12.5 eod feel fine no achy joints
    Eating ass is anabolic. .. Stick your tongue in and hold it there for 20 seconds! Wise words from
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  13. #13
    Elite Bullseye Forever's Avatar
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    Re: good article on exemestane (aromisan)

    25mg ed on cycle and 8mg/day off cycle on trt=awesome

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