Ozempic

[Kraken]

Ran across this, old news? Anyone tried it?


Ozempic and Weight Loss

 

[Kraken]

So, doing a bunch of googling it seems there are weight loss clinics pushing this, and similar, stuff. Apparently the clinical studies talk about losing 5% of body weight in a year. So if I'm 160 pounds, I can expect to lose a whopping 8 pounds after an entire year? People should be able to lose 8 pounds in 2 to 4 weeks on any normal, non drug related, diet.

I don't see the attraction, especially at the price point... Surly I'm missing something?

 

[JuiceTrain]

Sounds like something they give the fatties who sign up for a new gym membership at the beginning of the year....

 

[lifter6973]

So, doing a bunch of googling it seems there are weight loss clinics pushing this, and similar, stuff. Apparently the clinical studies talk about losing 5% of body weight in a year. So if I'm 160 pounds, I can expect to lose a whopping 8 pounds after an entire year? People should be able to lose 8 pounds in 2 to 4 weeks on any normal, non drug related, diet.

I don't see the attraction, especially at the price point... Surly I'm missing something?

Shit I can lose 8 pounds in a week without taking anything. I mean I have to put my mind to it but any time Ive beared down, Ive done it.

 

[buck]

So, doing a bunch of googling it seems there are weight loss clinics pushing this, and similar, stuff. Apparently the clinical studies talk about losing 5% of body weight in a year. So if I'm 160 pounds, I can expect to lose a whopping 8 pounds after an entire year? People should be able to lose 8 pounds in 2 to 4 weeks on any normal, non drug related, diet.

I don't see the attraction, especially at the price point... Surly I'm missing something?

The attraction for most people is they can loose weight without changing a thing. And their insurance may pay for it. In general i find people will try to take what ever the easy road is before they will attempt the harder path. Some guys will up the dose rather then work on improving their diet as an injection is easier the the alternative.

 

[eazy]

So if I'm 160 pounds

the market is 260lbs woman and 300+ male

 

[lifter6973]

the market is 260lbs woman and 300+ male

This is true, I would just lower it to 220+ for women

 

[Send0]

So I tried (semaglutide) it when I was sitting on my ass while recovering from my hernia surgery. My reasoning was I just wanted to see what it was like; in regards to how it effected hunger or blood glucose.

1. I took a low dose (0.25mg) for 8 weeks; it started working pretty much immediately.
2. I definitely never felt hungry while on it.
3. When I did eat I felt fuller for longer; actually made getting in my daily calories harder since I was not on a cut.
4. It took away any and all cravings for sweet or salty things I would get at night time.
5. My morning blood glucose improved by about 10pts (80 vs 90).

I could see how this could help an obese person who can't control their own appetites or cravings. I could also see how it could help satiate people while reducing their meal size. I think one of the ways it works is by slowing down gastric emptying.

I could also see how it could help recreationally for someone who chose to go on a very extreme cut.

The effects slowly did become less around week 6, and the instructions say to increase dosage as needed every 4 weeks because of this.

I won't be using it again, but it was interesting to see what it was all about. It definitely isn't a gimmick or all hype. It really does seem to work.

 

[GSDdad]

My wife is on Ozempic, prescribed through a hormonal specialist. She's been on it for about 3 months now.

At 38 yrs old, she had thyroid issues, early menopausal symptoms and some other hormonal issues that she's been struggling to find answers for, for the last 4 years. Along with steady weight gain each year, despite hurculean adherence to every type of eating plan conceived (high protein, keto, intermittent fasting, long fasting 24-48hr fasts, gluten elimination diets, blah blah blah) while putting in real work in the gym.

Doctors bounced her around over and over with the same "huh, we can't explain what's going on. Sorry."

Once the hormone specialist corrected thyroid, and hormonal imbalances (crashed estrogen and testosterone) she felt better, and wasn't gaining weight any more, but still wasn't losing. So the doc put her on Ozempic (semaglutide).

Over the last 3 months she's ratcheted up through the dosage protocol. Each dosage increase would see a pound or two drop, and then stall. Until she got to the 1.7mg dose. She's finally seeing steady losses at that dose.

For her, it's not the appetite suppressant. She doesn't need that, her issue isn't the behavioral side of eating. It's everything else it does: the increased insulin sensitivity, the reduced blood glucose, and reduced hepatic gluconegenesis. Semaglutide also seems to promote more fat oxidation. Those seem to have had a big impact in her ability to drop weight.

So for her, it's been absolutely phenomenal. 30lbs in 3 months, with her diet and training being relatively unchanged.

The side effects are no joke though. Early on she had some rough lower GI issues. Those have since resolved. But she's stuck with varying levels of nausea through most of the week. It's worse the day after injection, and slowly dissipates throughout the week until the next injection. It's at it's worst in the mornings, and gets better as the days goes on. It's not uncommon for her to have to step away two or three times during our morning workouts to puke.

The gastric emptying slowdown is extreme as well. Those 6am workout vomits often have some or most of the last meal she ate at 6 or 7pm the night before.

The side effects are rough, but, for now, the juice is worth the squeeze, when nothing else for the last four years seemed to make a dent.

Does it have a place in this world? Maybe as an appetite suppressant during prep? I dunno. I've never competed so I'd just be talking out of my ass. But for the general pop who can't control their eating, or the smaller percentage who have actual hormonal /metabolic issues that are making weight loss difficult, yeah it has a place.

I have never tried it. But I can try to answer questions if there are any. Or I can ask her and relay back.

 

[Kraken]

Great comments guys, thanks!

 

[Badleroybrown]

My daughter is on some king called selexa..
she has lost almost 30lbs in 2-1/2 months.
It blunts her hunger and helps her to curb her appetite.
My ins pays for it. If it did not its
Like 1200$ a month..
She does not work out but I will go shared and say if she did the loss would be greater.
But she is only 18 and insecure with her body…


My wife has used it with no work for her..
She has also Tried the above the OP mentioned.
Made her sick and nauseous..
Had to stop.

She has a hard time losing weight but she is also on a ssri for anxiety and depression and this drugs cause weight gain.
It’s water and it does something I. The brain to slow metabolism…
It also makes you crave sugar and makes you very insulin resistant.

I love her no matter what and I would rather have her a little chunky and happy then fit and depressed.

Why would anyone who does what we do resort to a medicine like this . Close your mouth do some cardio and train insane. All else falls into place..

 

[Angryshitter]

My daughter is on some king called selexa..
she has lost almost 30lbs in 2-1/2 months.
It blunts her hunger and helps her to curb her appetite.
My ins pays for it. If it did not its
Like 1200$ a month..
She does not work out but I will go shared and say if she did the loss would be greater.
But she is only 18 and insecure with her body…


My wife has used it with no work for her..
She has also Tried the above the OP mentioned.
Made her sick and nauseous..
Had to stop.

She has a hard time losing weight but she is also on a ssri for anxiety and depression and this drugs cause weight gain.
It’s water and it does something I. The brain to slow metabolism…
It also makes you crave sugar and makes you very insulin resistant.

I love her no matter what and I would rather have her a little chunky and happy then fit and depressed.

Why would anyone who does what we do resort to a medicine like this . Close your mouth do some cardio and train insane. All else falls into place..

Well to respond to you're question of why anyone would use it. Is because for someone like me losing weight and keeping it off is such a bitch that you litterally can't go out to party's or social events where you know youll have to eat foods that will open the flood gates. Or there are times when I litterally cannot sleep despite how burnt out I am because food cravings keep you up at night where you have to decide between blowing your diet or getting actual sleep. You can't focus at work or be present. The cravings and desire to eat can be so extreme it physically impairs your quality of sleep. I remember I'd wake up to piss and find my self half asleep eating food not even fully aware of what I was doing. Hormones / the brain it's a powerful thing. Semaglutide shuts the fatass voice in the back of my brain allowing me to live my life. I lost 50 lbs without it. But it wasn't sustainable to keep it off. Semaglutide is allowing me to live my life again.

It's hard to explain but closing your mouth and putting the fork down isn't allways the case. If you know , you know... but what I can say is with Semaglutide I find myself having the same mindset.."it's just food. It's not that hard to not eat" then I remember I was there myself. Many many MANY times...

 

[Badleroybrown]

Bro I am glad it works for you..
If this is what it takes to attain your goals then by all means.

For me when I am trying to get some pounds off I will eat anything that keeps me full.

Since I was out into a diet by someone back in March I started to eat a lot of fruits.
Now when I am in bed at night and I have cravings my go to is apples..
I find that the cold crispy was if a apple satisfying and if need be I will eat 2.

Bro dieting and losing weight is a hard thing to do..
So whatever works to get the job done do it.

 

[crido887]

I have ran semaglutide(Ozempic). stalls out about 3 months. I stopped using it and started bulking so the hunger rebound would go toward muscle gains. After this cycle I will do mounjaro(Tirzepide) for a little bit to cut up even further.

Alot of interesting information on GLP agonists.

improves lipolysis, prevents muscle catabolism, browns white fat.

 

[Angryshitter]

Bro I am glad it works for you..
If this is what it takes to attain your goals then by all means.

For me when I am trying to get some pounds off I will eat anything that keeps me full.

Since I was out into a diet by someone back in March I started to eat a lot of fruits.
Now when I am in bed at night and I have cravings my go to is apples..
I find that the cold crispy was if a apple satisfying and if need be I will eat 2.

Bro dieting and losing weight is a hard thing to do..
So whatever works to get the job done do it.

He'll yeah man. Honestly at this point I'm willing to do whatever drug it takes to make it possible. I'd rather die then be fat af again lol. But that being said I do think people lean too heavy on this drug. The guy at my clinic pushed me to a higher dose because he wanted to see "faster weight loss" that pissed me off because I was still losing weight. It was just slow. But I was alright with that. And don't want it to be effortless. it's important to me to still practice discipline and self control. It's a mental muscle that needs to stay strong. Now my dose is increased and I'm under eating. I'm exposing myself to more tolerance. Fuck this and fuck him I'm ordering it UGL now.
Weird as it may sound I still want to have to fight just a LITTLE to keep it off. I just want to use it to take the edge off. Not annihilate my hunger. They say it's a drug that can work forever. I call bullshit. Like with everything tolerance and effectiveness will most likely dwindle over time so I want to stay on my toes mentally.
As with you I like to stick to low calorie high volume foods. It's how I lost the last half of my weight. Honestly just being aware of my calorie intake has been the biggest help. Like with anything if you don't have a back up plan then your fucked lol. If this shit ever gets banned or there's a huge shortage then 1,000s of people will be back to square one unless they've developed some kind of knowledge of how to keep the weight off. Despite the mental stress it takes.
But your absolutely right at the end of the day whatever works to keep from being obese is worth it. At least to me.

 

[Angryshitter]

I have ran semaglutide(Ozempic). stalls out about 3 months. I stopped using it and started bulking so the hunger rebound would go toward muscle gains. After this cycle I will do mounjaro(Tirzepide) for a little bit to cut up even further.

Alot of interesting information on GLP agonists.

improves lipolysis, prevents muscle catabolism, browns white fat.

Hey man. So when you come off it dose your hunger return to normal? Or is there infact an overcompensation of appetite in extreme hunger? Like I notice a large hunger rebound when I come off of stimulants for appetite suppression I can litterally eat the God damn fridge. Lol just curious so I can prepare myself for when I come off this shit lol

 

[crido887]

its a little hard to tell. I was running DECA so I was getting hungrier.

The studies say the fat people regained their weight, but probably because of their unhealthy lifestyle.

my wife dropped 20. regained 5. and hasnt moved. She was 140. I Think she was 125 in my profile pic.

 

[Angryshitter]

its a little hard to tell. I was running DECA so I was getting hungrier.

The studies say the fat people regained their weight, but probably because of their unhealthy lifestyle.

my wife dropped 20. regained 5. and hasnt moved. She was 140. I Think she was 125 in my profile pic.

First of all. That's your wife in your profile picture? hats off you to my dude

Second.. yeah that's what my thinking Is too. I'm hoping to really hit the ground running.
But that was a big worry of mine so I'm glad your wife is having success that makes me excited.
Also did she taper down? Or just cold turkey it? What dose was she on and for how long?
That's the big red flag for me about this drug. I only ever hear about the weight loss. You don't hear much about the aftermath of when people come off. So I really appreciate the feedback

 

[crido887]

First of all. That's your wife in your profile picture? hats off you to my dude

Second.. yeah that's what my thinking Is too. I'm hoping to really hit the ground running.
But that was a big worry of mine so I'm glad your wife is having success that makes me excited.
Also did she taper down? Or just cold turkey it? What dose was she on and for how long?
That's the big red flag for me about this drug. I only ever hear about the weight loss. You don't hear much about the aftermath of when people come off. So I really appreciate the feedback

she stopped. she regained some of the water weight and freaked out. injected herself with 0.25mg of tirzepide lol.

she has been fine since then

another friend dropped 30 lbs over 3-4 months. she has stalled. its a friends wife. she doesnt have an ass and wants one. I told her to get off and go take a low dose of anavar with alot of squats. doubtful she will do so.

I have another friend who dropped 12 lbs over 3 months with no exercise but she has poor eating habits.... really bad... I told her she will regain the weight when she gets off.

 

[Badleroybrown]

my wife dropped 20. regained 5. and hasnt moved. She was 140. I Think she was 125 in my profile pic.