The effect that LH has on P450scc can be mimicked by pregnenolone supplementation.
These 2 are what really concerns me about shutting down LH production. Humans have evolved with this hormone, and the body expends energy producing it for a reason. I don't like it being absent. I'm thinking about giving hCG another shot. Even low dose would be beneficial.
I don't think John Crysler thought that using HCG on TRT would ''activate'' the testicles.I've followed and read all of his books and publications. From what I know he added HCG on TRT just to ''make testosterone works better'' , that was his very disputable theory but there is no scientific evidence suggestion that . I remember he also changed idea about the best testosterone delivery system , at first he said vials then , after few years , he switched on gel wich he believed was the best way to administer testosterone to the body. I tried gel for a while but it was a disaster.
I didn't know LH was responsable for nerve generation, can you send some sources about it ? If I want regenerate my nerve I'm gonna use some peptides or IGF - GH .
No I'm serious, many studies about it. https://www.ncbi.nlm.nih.gov/pmc/ar...nd that IGF-1,after nerve injury during aging.
And how about a study that was done on humans. Better yet, how about something that has at least gone into clinical trials for human testing?
As i was a patient of Dr. Crisler for years my view of his treatments may be different then your own. He used HCG as a stand alone at one time for some, as a daily adjutant for some, and multiple times a week for others. His views on things changed as most have over the last 20+ year i have been on Dr. prescribed TRT . And i assume it will continue to change and think we are not close to having the optimal methods. And that does not mean that going back to something used in the past may not be better. some times you change then chane back. He believed in keeping the p450 open to get cholesterol down stream the last i spoke with him. So it would seem he had more ideas about HCG then just making (activating)T. He was into trying to keep all the bodies functions working at an optimal younger mans levels in my conversations . He found gels to work for many if not most but you also have to take into consideration what people are willing to do. And people such as me didn't absorb well. 50mg/day of gel raised my levels about 100 points. I was on gels when i started with him and he changed me to injections. He did not have a cookie cutter approach.
Why would i mimic something with 1 supplement when i can get multiple positive(posssibly) effects by taking 1 different thing.
If i can get that effect by using HCG, which mimics LH, which a healthy body makes on a regular basis till we start screwing with hormones, and get other plosive effects as well i tend to want to take the more natural substance that will give me multiple benifits. If people took HCG regularly they may never have needed the peptide as the nerves may have stayed healthier to start with. This is all conjecture of course, just for discussion so each can make the best decision for them selves.
I am far from a scientist but these looked promising to me. For nerves as well as the lining of arteries etc. Those with a big brain may get more from them then i did.
karger.com
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
academic.oup.com
Do you have nerve damage?
Because hCG gives some people bad side effects, myself included.
I certainly have less then optimal nerve function from accidents and heavy lifting and spinal issue. So the HCG may have been a benefit and kept it from getting worse or not. No way to know. One offs or tiny studies do not prove anything in my book. I believe that keeping the body functioning at as healthy of a level such as a young man is, is probably best in general. But that is just opinion too. As normal or upper normal levels of HGH in mice mean shorter life spans. But then there is quality vs quantity for each person to consider for themselves.
Then you shouldn't take it. I assumed we were talking about in general and not covering every case for every person. There is probably the rare individual that rejects their own LH but in general people do better with it it seems.
I posted it for information's sake, since you aren't the only one who reads these threads.
Same as my posts. I was just replying to what to tagged me in.
I also have bad response from HCG if i mixed it with Testosterone. My estrogen levels go sky high and I don't see any benefit in terms of testiculare reactivation or libido boost. Different story if I take HCG one or two months after stopping TRT , then I see something in my blood work with E2 , FSH , LH , PRL and Test in the range. Another issue to consider, like GreenAmine said, is the cost and I add the difficulty to find legit HCG expecially if you are not living in US or Europe. In this case pregnenolone would surely be a better choice.
