Oakley6575
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Going balls deep into homebrewing, so I figured I would log it so I can share my mistakes and successes. Hopefully this helps someone in the future. This is all for personal use.
600mg/mL Injectable L-Carnitine:
So my first attempt was bullshit. Did everything wrong and now have a respect/hatred for syringe filters. I attempted 100mL with the following recipe:
42mL DA (Distilled Water)
60g Bulk L-Carnitine
1mL BA (Benzyl Alcohol)
In a 500mL media bottle, I added 42mL of DA, then 1mL of BA, and then started slowly adding L-Carnitine powder. Shaking as I went, I got all the powder in the media bottle and then went to town mixing. There were a lot of clumps that were very hard so shaking the mixture didn't do shit in breaking them up. I took a long bartenders metal mixing spoon and broke them up, mixed, broke more up, mixed, and on and on and on until all the powder had dissolved. At this point, I took a new sterile 100mL vial, and added a 23g vent needle. I drew up 50mL of of solution in a 60mL vial and added a .22µm pvdf luer lock filter to the end of it. Then I added a 23g needle to that set up and inserted it into the vial. Now anyone who has done this knows how fucked I am. But I didn't, so enjoy my misery. I basically had to park a fucking car on top of the syringe for anything to come through the filter. I fought it for a while and got around 5mL through the filter before I pulled the plug. Basically just threw everything in the garbage and went upstairs and cried for a couple hours.
Once I composed myself, I came back down for a second attempt. This time I decided to only brew 30mL with the following recipe:
12.6mL DA
18g Bulk L-Carnitine
0.3mL BA
So this time, everything went smooth. I made a few tweaks that obviously needed to happen. Once all the powder was in with the DA and BA, I had large hard clumps again so I added a little bit of heat, and they went away immediately. I shook everything up and it mixed very easily. I know you don't need heat for L-carnitine but it helps a shit ton. Next thing I did was drew the solution up in a 3mL syringe instead of a large syringe. Added my vent needle to the 30mL vial, put on my pvdf filter and needle, and started pushing... Went through the syringe filter with ease. It literally took 10-15 seconds to empty the 3mL syringe. Once empty, I just unscrewed the syringe, leaving the needle and syringe filter in the vial, drew up 3mL more, and reattached the syringe to the filter. Empty, fill, empty, fill, etc. Even though you have to do that process a bunch of times, it goes very fast and is super easy. Lesson learned.
That 30mL vial will be drawn from and injected tomorrow morning so I'll report back with pip or any issues I have.
Also, I'm going to keep this log going with all the info I have during all my homebrews. My next plan is to brew Test Cyp and make liquid oral suspensions with Humco for daily tadalafil and aromasin to have on hand.
600mg/mL Injectable L-Carnitine:
So my first attempt was bullshit. Did everything wrong and now have a respect/hatred for syringe filters. I attempted 100mL with the following recipe:
42mL DA (Distilled Water)
60g Bulk L-Carnitine
1mL BA (Benzyl Alcohol)
In a 500mL media bottle, I added 42mL of DA, then 1mL of BA, and then started slowly adding L-Carnitine powder. Shaking as I went, I got all the powder in the media bottle and then went to town mixing. There were a lot of clumps that were very hard so shaking the mixture didn't do shit in breaking them up. I took a long bartenders metal mixing spoon and broke them up, mixed, broke more up, mixed, and on and on and on until all the powder had dissolved. At this point, I took a new sterile 100mL vial, and added a 23g vent needle. I drew up 50mL of of solution in a 60mL vial and added a .22µm pvdf luer lock filter to the end of it. Then I added a 23g needle to that set up and inserted it into the vial. Now anyone who has done this knows how fucked I am. But I didn't, so enjoy my misery. I basically had to park a fucking car on top of the syringe for anything to come through the filter. I fought it for a while and got around 5mL through the filter before I pulled the plug. Basically just threw everything in the garbage and went upstairs and cried for a couple hours.
Once I composed myself, I came back down for a second attempt. This time I decided to only brew 30mL with the following recipe:
12.6mL DA
18g Bulk L-Carnitine
0.3mL BA
So this time, everything went smooth. I made a few tweaks that obviously needed to happen. Once all the powder was in with the DA and BA, I had large hard clumps again so I added a little bit of heat, and they went away immediately. I shook everything up and it mixed very easily. I know you don't need heat for L-carnitine but it helps a shit ton. Next thing I did was drew the solution up in a 3mL syringe instead of a large syringe. Added my vent needle to the 30mL vial, put on my pvdf filter and needle, and started pushing... Went through the syringe filter with ease. It literally took 10-15 seconds to empty the 3mL syringe. Once empty, I just unscrewed the syringe, leaving the needle and syringe filter in the vial, drew up 3mL more, and reattached the syringe to the filter. Empty, fill, empty, fill, etc. Even though you have to do that process a bunch of times, it goes very fast and is super easy. Lesson learned.
That 30mL vial will be drawn from and injected tomorrow morning so I'll report back with pip or any issues I have.
Also, I'm going to keep this log going with all the info I have during all my homebrews. My next plan is to brew Test Cyp and make liquid oral suspensions with Humco for daily tadalafil and aromasin to have on hand.